Nitrosylcobalamin, New Drug Overcome Cancer

Researchers at the Cleveland Clinic have shown promising results for cancer treatment. The reason, a new anticancer drug tested in dogs suffering from cancer, was able to deal with cancer without side effects like poison or a disadvantage. These drugs, they explained, would be an effective treatment for promising new therapies to treat cancer in humans.

Because of this new discovery, Joseph A. Bauer, PhD, Center of Hematology / Oncology Molecular Therapeutics at the Cleveland Clinic, was awarded outstanding at the 237th annual meeting of the American Chemical Society.

Bauer's team has succeeded in this story begins with Oscar, age 10, male dog who has cancer is very aggressive. Cancer is known as adenocarcinoma bag. Oscar chemotherapy and radiotherapy, but failed. Oscar convicts can not survive for 3 months and lose the ability to walk.

In addition, Bauer's team gave the drug against cancer killer Oscar innovation called nitrosylcobalamin (NO-CBL). The results are very encouraging. In two weeks, Oscar cancer has improved and he could walk again.

Trojan horse "to Cancer

NO-CBL drugs fight cancer, as the Trojan horse principle. Trojan is a destructive substance hidden in something that looks harmless.

New medicine against cancer is also almost the same principle. cancer killer and drug addiction, known as nitric oxide is incorporated in the tablets of vitamin B12. The substance, called receptors on the cell surface and vitamins to help pull in the cell. Cancer cells grow faster in the presence of B12 receptors. NO-CBL using this receptor in the cells and release of nitric oxide. Nitric oxide is killing the cancer cells from within.

Based on the news release from the American Chemical Society, experts have tried for over 60 years developed a Trojan horse with vitamin B12 like this to fight cancer.

Tim Bauer also reported similar results with success on two other dogs. Ultrasound and MRI showed a significant reduction in tumor size in the three dogs studied.

The use of n-CBL for 9 months to reduce the size of the cancer by 40% in dog named Buddy. Dogs that had suffered nerve damage in his right foot behind her again able to walk. This treatment has also shown encouraging results in dogs Schnauzwer giant female who developed thyroid cancer. Cancer before and no longer have this currently experiencing a reduction in size of up to 77% in less than 10 weeks. The team is treating the dog the fourth, a golden retriever named Haley.

The team intends to cure cancer in 10 dogs, then get FDA approval for testing in humans. "In human genetics with the same dog that will facilitate the FDA approval for human trials," said Bauer.